Participating Labs

The Al-Hashimi group develops quantitative and predictive models of RNA cellular activity through the determination of RNA conformational ensembles showing how their 3D structures vary with time.

The Basu lab is interested in studying RNA surveillance, noncoding RNA processing and DNA alteration events in lymphocytes

The Batut lab studies the interplay between non-coding RNAs, 3D genome organization and gene regulation in developing systems.

The Berchowitz lab examines how various types of condensates give rise to emergent properties beyond those of the constituent proteins and how healthy cells regulate these structures.

The Chung lab is interested in understanding how RNA sensing shapes human immune responses in infection, autoimmunity, and neural disease

The Dworkin lab studies regulation of translation during nutrient limitation in bacteria, with a particular focus on the phenomenon of ribosome dimerization.

The Frank lab is interested in time-resolved cryo-electron microscopy of the translational machinery in bacteria and eukaryotes

The Gaublomme lab develops optical pooled CRISPR screens with multi-omic in situ readout to understand cellular function and intercellular communication.

The Gennarino lab is an RNA Neurobiology lab that moves between patients, animal models, and wet lab experiments to understand how defects in RNA-binding proteins and post-transcriptional RNA processing cause neurological diseases.

Ghabrial lab is interested in tricRNAs and the role of mTOR and Archease/tRNA ligation complex in tRNA processing.

The Goff lab studies retrovirology; HIV-1; murine leukemia viruses; endogenous retroviruses; host restriction factors.

The Gonzalez lab focuses on the thermodynamics, kinetics and structures of biomolecular assemblies and molecular motors, with specific emphasis on the ribosome and protein synthesis.

The Hunt lab employs diverse biophysical and molecular biological methods to elucidate the mechanisms of complex biomolecular processes including the influence of synonymous codon variations and ABCF proteins on mRNA translation and the structural mechanics of transmembrane transporters.

The Jovanovic lab's overarching research goal is to understand the principles and mechanisms by which post-transcriptional regulation controls the dynamics of gene expression

The Kieft lab is interested in how the complex and dynamic 3-D structures of RNA, and their interactions with other molecules, lead to diverse biological functions.

The Landweber lab studies RNA-mediated epigenetic inheritance and RNA-guided genome reorganization during development and evolution

The Levo lab combines experimental and computational approaches to study the dynamic, multilayered control of gene expression in the context of genome organization.

The Liao lab is interested in mRNA localization and translation in the brain.

The Lomvardas lab is exploring the non-coding functions of olfactory receptor mRNAs in the assembly of multi-enhancer genomic hubs and the regulation of olfactory receptor gene choice.

The Maniatis lab is interested in understanding fundamental mechanisms of transcription and RNA splicing in the nervous system, and how these mechanisms bear on neuronal connectivity and neurodegenerative diseases.

The Manley lab is interested in studying mechanisms of mRNA processing: Regulation and links to human disease.

The Pellizzoni lab is interested in Neuroscience, Neurodegeneration and the study of RNA-binding proteins and non-coding RNA regulatory networks in neurological disorders.

The Sanbonmatsu lab integrates molecular simulation, cryo-EM and biochemistry to understand the mechanism of ribosomes, riboswitches and non-coding RNAs.

In the Steckelberg lab, we combine RNA biology, structural biology and virology to study how viruses manipulate cellular gene expression.

The vision of the Sternberg lab is to explore and exploit new molecular mechanisms at the host-transposon interface, with a special focus on roles played by transposases, nucleases, and non-coding RNAs.

The Tong lab uses structural biology techniques to study the molecular mechanism of RNA 3'-end processing, 5' decapping, degradation and related events

The Wu lab is interested in decoding and targeting RNA in health and disease

The Zaccara lab is dedicated to investigating the fundamental mechanisms that regulate mRNA fate in both normal and disease states, with a specific focus on understanding the role of RNA modifications

The Zhang lab is interested in protein-RNA interaction, neuronal alternative splicing regulation & function, RNA-based precision medicine.